
Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 10mg | ||||
360 pill | 10mg | £160.78 | £0.45 | |
180 pill | 10mg | £85.60 | £0.48 | |
120 pill | 10mg | £61.78 | £0.51 | |
90 pill | 10mg | £48.38 | £0.54 | |
60 pill | 10mg | £34.23 | £0.57 | |
30 pill | 10mg | £17.86 | £0.59 | |
Dosage: 25mg | ||||
180 pill | 25mg | £127.28 | £0.71 | |
120 pill | 25mg | £89.32 | £0.74 | |
90 pill | 25mg | £72.20 | £0.80 | |
60 pill | 25mg | £52.84 | £0.88 | |
30 pill | 25mg | £29.02 | £0.96 | |
Dosage: 50mg | ||||
180 pill | 50mg | £210.65 | £1.17 | |
120 pill | 50mg | £147.38 | £1.23 | |
90 pill | 50mg | £117.60 | £1.31 | |
60 pill | 50mg | £84.85 | £1.41 | |
30 pill | 50mg | £48.38 | £1.61 | |
Dosage: 75mg | ||||
90 pill | 75mg | £170.46 | £1.89 | |
60 pill | 75mg | £121.33 | £2.02 | |
30 pill | 75mg | £74.43 | £2.47 |

Endep Description
Overview of Endep
Endep, known generically as amitryptyline, is a medication commonly prescribed in the UK to treat various mental health conditions, especially depression. It also helps in managing certain types of nerve pain, which can be particularly troublesome for those suffering from conditions like diabetic neuropathy. Endep belongs to a class of drugs called tricyclic antidepressants. These work by affecting the balance of chemicals in the brain, which can improve mood and relieve pain.
How Endep Works
The medication primarily influences neurotransmitters such as serotonin and noradrenaline, helping to restore their normal activity in the brain. This action can lift mood, increase energy levels, and improve overall wellbeing. When used for nerve pain, Endep is thought to reduce the sensitivity of nerve signals, lessening discomfort. It’s usually taken once a day, often at bedtime, to minimise side effects like drowsiness.
Benefits and Effectiveness
Many patients in the UK report significant improvements in their symptoms after starting Endep. It can be particularly effective for those who haven't responded well to other antidepressants. Besides mood enhancement, Endep’s ability to ease nerve-related pain makes it a versatile medication. Its sedative properties can also help some people with insomnia related to depression or anxiety. However, individual response varies, and it may take several weeks before noticeable benefits are felt.
Possible Side Effects
While Endep can be beneficial, it’s important to be aware of potential side effects. Common ones include dry mouth, drowsiness, dizziness, and blurred vision. Some people may experience constipation or weight gain. In rare cases, it can cause heart rhythm disturbances or allergic reactions. It’s crucial to discuss medical history with a healthcare professional before starting Endep. Regular monitoring may be advised, especially at the beginning of treatment or when doses are adjusted.
Usage in the UK Healthcare System
In the UK, Endep is available via prescription from general practitioners or specialists. Pharmacists play an essential role in providing guidance on how to take it safely. It’s usually advisable to follow the prescribed dose strictly and not to stop or change doses without consulting a healthcare professional. Patients are also encouraged to report any adverse effects or concerns promptly during treatment.
Considerations and Precautions
Patients with certain health conditions, such as heart problems, glaucoma, or urinary retention, should inform their doctor before starting Endep. It can also interact with other medications, including other antidepressants, certain antibiotics, and blood thinners. Alcohol consumption should be limited, as it can increase side effects like drowsiness. Women who are pregnant or breastfeeding should discuss risks and benefits with their healthcare provider.
Patient Experiences and Perspectives
Many UK patients find Endep helpful once they adapt to the medication. Some note a significant improvement in their mood and reduction in nerve pain within a few weeks. However, others may experience initial drowsiness or dry mouth, which often lessen over time. It’s common for patients to appreciate the drug's effectiveness, especially when other treatments have failed. As with all medications, individual experiences vary, and ongoing communication with healthcare providers is vital to optimise outcomes.