| Package | Dosage | Price | Price per Dose | |
|---|---|---|---|---|
| Dosage: 250mg | ||||
| 360 pill | 250mg | £209.16 | £0.58 | |
| 180 pill | 250mg | £110.91 | £0.62 | |
| 120 pill | 250mg | £79.64 | £0.66 | |
| 90 pill | 250mg | £64.75 | £0.72 | |
| 60 pill | 250mg | £48.38 | £0.81 | |
| 30 pill | 250mg | £27.53 | £0.91 | |
| Dosage: 500mg | ||||
| 270 pill | 500mg | £178.64 | £0.66 | |
| 180 pill | 500mg | £124.30 | £0.69 | |
| 120 pill | 500mg | £90.06 | £0.75 | |
| 90 pill | 500mg | £72.20 | £0.80 | |
| 60 pill | 500mg | £55.08 | £0.92 | |
| 30 pill | 500mg | £33.49 | £1.12 | |
Disulfiram Description
Introduction to Disulfiram
Disulfiram is a medication primarily used to support the treatment of chronic alcoholism. It works by producing an adverse reaction when alcohol is consumed, which discourages individuals from drinking. Since its development in the 1940s, Disulfiram has been a cornerstone in alcohol dependence management, especially for patients committed to abstinence. It is available by prescription and should always be used under medical supervision to ensure safety and effectiveness.
How Disulfiram Works
The active ingredient in Disulfiram inhibits the enzyme aldehyde dehydrogenase, which is involved in metabolizing alcohol in the body. When a person consumes alcohol while on Disulfiram, they experience unpleasant effects such as nausea, vomiting, headache, flushing, and rapid heartbeat. These symptoms serve as deterrents, helping individuals resist the urge to drink. This approach can be quite effective when combined with counseling and support, helping patients maintain sobriety over time.
Administration and Dosage
Disulfiram is typically administered once daily in tablet form. The dosage varies depending on the patient's condition and response. It is essential to start the medication only after the individual has abstained from alcohol for at least 12 hours. Patients should avoid alcohol-containing products, including certain foods, medicines, mouthwashes, and cosmetics, to prevent accidental reactions. Regular monitoring by a healthcare professional is necessary to adjust dosage and ensure proper use.
Possible Side Effects and Precautions
While Disulfiram is generally safe when used correctly, it can cause side effects. Common reactions include skin rash, drowsiness, and gastrointestinal discomfort. Severe but rare side effects can include liver toxicity, seizures, and allergic reactions. Patients with liver disease, heart problems, or mental health disorders should discuss their conditions with a doctor before starting Disulfiram. It is crucial to follow medical advice closely and report any adverse symptoms promptly.
Effectiveness and Limitations
Disulfiram can be highly effective for some individuals struggling with alcohol dependence. It helps reinforce abstinence through negative reinforcement and can be particularly useful when combined with counseling and behavioral therapy. However, it is not a cure for alcoholism, and its success depends heavily on the patient’s motivation and commitment. Missing doses or drinking alcohol while on Disulfiram can undermine its effectiveness and increase health risks.
Conclusion
Disulfiram remains a valuable tool in the management of alcohol dependence when used responsibly. Its mechanism of creating an unpleasant reaction to alcohol helps motivate patients to stay sober. Nonetheless, it requires careful supervision, adherence to medical guidance, and commitment to treatment plans. Patients should always communicate openly with their healthcare provider to ensure safe and effective use of this medication, and to address any concerns or side effects that may arise during therapy.