Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 5mg | ||||
270 pill | 5mg | £131.00 | £0.48 | |
180 pill | 5mg | £100.48 | £0.56 | |
120 pill | 5mg | £75.92 | £0.63 | |
90 pill | 5mg | £64.01 | £0.71 | |
60 pill | 5mg | £49.87 | £0.83 | |
30 pill | 5mg | £31.26 | £1.03 | |
Dosage: 10mg | ||||
270 pill | 10mg | £261.27 | £0.97 | |
180 pill | 10mg | £209.16 | £1.16 | |
120 pill | 10mg | £148.12 | £1.24 | |
90 pill | 10mg | £119.84 | £1.33 | |
60 pill | 10mg | £93.78 | £1.56 | |
30 pill | 10mg | £64.75 | £2.17 |

Hydrochlorothiazide Description
Overview of Hydrochlorothiazide
Hydrochlorothiazide is a widely used medication primarily prescribed to treat high blood pressure (hypertension) and fluid retention (edema). It belongs to a class of drugs called thiazide diuretics, which help the body eliminate excess salt and water, thereby lowering blood pressure and reducing swelling. This medication is often recommended as part of a comprehensive treatment plan to control hypertension, which can help prevent more serious health problems such as strokes, heart attacks, and kidney issues.
How Hydrochlorothiazide Works
The mechanism of action of hydrochlorothiazide involves affecting the kidneys' ability to reabsorb sodium and chloride. By inhibiting specific transporters in the distal tubules of the nephron, the medication increases the excretion of sodium, chloride, and water. This diuretic effect reduces blood volume, which in turn decreases the pressure on arterial walls. It also promotes the excretion of excess fluids in cases of edema. The result is a gradual decrease in blood pressure, making it an effective option for managing hypertension.
Effectiveness and Usage
Hydrochlorothiazide has been proven effective in lowering blood pressure levels in many patients. It is often used alone or in combination with other antihypertensive drugs. For edema, it helps reduce swelling associated with heart failure, liver disease, or kidney problems. The medication is usually taken once daily, with the dosage tailored to individual patient needs. Regular monitoring of blood pressure and kidney function is essential while using this medication to ensure its effectiveness and safety.
Potential Side Effects
While hydrochlorothiazide is generally well-tolerated, it can cause side effects in some people. Common adverse effects include increased urination, electrolyte imbalances such as low potassium or sodium levels, dizziness, and dehydration. Some patients may experience changes in blood sugar levels or an increase in blood uric acid, which could potentially trigger gout. Less common but more serious side effects include allergic reactions, severe dehydration, or disturbances in kidney function. Patients are advised to seek medical advice if they experience persistent or severe side effects.
Precautions and Interactions
Before starting hydrochlorothiazide, it is important to inform your healthcare provider about any existing health conditions, especially kidney or liver problems, gout, or electrolyte imbalances. The medication may interact with other drugs such as digoxin, lithium, or diabetes medications, altering their effectiveness or increasing the risk of adverse reactions. Regular blood tests are often recommended to monitor electrolyte levels and kidney function during treatment. Patients should also be cautious about their salt and fluid intake to prevent dehydration and electrolyte disturbances.
Conclusion
Hydrochlorothiazide remains a cornerstone medication for managing hypertension and edema due to its proven efficacy and affordability. Proper usage, regular monitoring, and awareness of potential side effects are essential for safe and effective treatment. When prescribed and used correctly, it can significantly contribute to better cardiovascular health and improved quality of life. As with any medication, it’s crucial to follow your healthcare provider’s instructions and report any unusual symptoms or concerns promptly.